SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
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<
>
<=
>=
starts with
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in
not in
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!=
<
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<=
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starts with
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not in
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<
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<=
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starts with
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in
not in
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<
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<=
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not in
=
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starts with
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not in
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<
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<=
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starts with
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not in
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<
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<=
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starts with
contains
in
not in
=
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<
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<=
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starts with
contains
in
not in
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<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
=
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<
>
<=
>=
=
!=
<
>
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>=
=
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<
>
<=
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=
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<
>
<=
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1CHO_EFG_I
NI36I
NI33I
COR
Pr/PI
Pr/PI
5E-12
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36M
NI33M
COR
Pr/PI
Pr/PI
3.7E-12
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36D
NI33D
COR
Pr/PI
Pr/PI
9.09E-13
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36K
NI33K
COR
Pr/PI
Pr/PI
2.7E-10
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36Q
NI33Q
COR
Pr/PI
Pr/PI
3.85E-12
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36E
NI33E
COR
Pr/PI
Pr/PI
2.7E-10
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36H
NI33H
COR
Pr/PI
Pr/PI
1.52E-12
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36F
NI33F
COR
Pr/PI
Pr/PI
2.86E-10
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36R
NI33R
COR
Pr/PI
Pr/PI
7.69E-11
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
NI36Y
NI33Y
COR
Pr/PI
Pr/PI
4E-10
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
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