SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
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PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
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7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
2J0T_A_D
TD2S,VD4A
TD2S,VD4A
COR,RIM
2J0T_A_D
3.3E-09
4E-10
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
298(assumed)
None
None
None
None
IAFL
2J0T_A_D
TD2R,VD4I
TD2R,VD4I
COR,RIM
2J0T_A_D
n.b
4E-10
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
298(assumed)
None
None
None
None
IAFL
2J0T_A_D
TD2S,VD4A,SD68Y
TD2S,VD4A,SD68Y
COR,RIM,COR
2J0T_A_D
1.5E-08
4E-10
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
298(assumed)
None
None
None
None
IAFL
2J0T_A_D
CD1S,FD12Y
CD1S,FD12Y
COR,INT
2J0T_A_D
1.8E-06
1.5E-09
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
305
None
None
None
None
IAFL
2J0T_A_D
TD2A
TD2A
COR
2J0T_A_D
2.09E-06
1.5E-09
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
305
None
None
None
None
IAFL
2J0T_A_D
MD66A
MD66A
RIM
2J0T_A_D
2.4E-08
1.5E-09
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
305
None
None
None
None
IAFL
2J0T_A_D
VD69I
VD69I
COR
2J0T_A_D
5.7E-09
1.5E-09
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
305
None
None
None
None
IAFL
2J0T_A_D
VD69T
VD69T
COR
2J0T_A_D
1.32E-08
1.5E-09
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
305
None
None
None
None
IAFL
2J0T_A_D
VD69A,AD103V
VD69A,AD103V
COR,INT
2J0T_A_D
4.9E-09
1.5E-09
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
305
None
None
None
None
IAFL
2J0T_A_D
CD70S
CD70S
SUP
2J0T_A_D
2.16E-06
1.5E-09
MMP1 Interstitial collagenase
Metalloproteinase inhibitor 1
305
None
None
None
None
IAFL
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