SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
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PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
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7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
2AJF_A_E
NE479K
NE151K
COR
2AJF_A_E
4.84E-07
1.62E-08
Human Angiotensin-converting enzyme 2
SARS spike protein receptor binding domain
298(assumed)
5.73E+04
7.12E+04
2.77E-02
1.16E-03
None
None
None
None
SPR
2AJF_A_E
TE487S
TE159S
COR
2AJF_A_E
3.52E-07
1.62E-08
Human Angiotensin-converting enzyme 2
SARS spike protein receptor binding domain
298(assumed)
3.88E+04
7.12E+04
1.32E-02
1.16E-03
None
None
None
None
SPR
2A9K_A_B
GB99D
GB55D
COR
2A9K_A_B,5XCO_A_B
3E-06
6E-08
Ras-related protein Ral-A
Mono-ADP-ribosyltransferase C3
310
-25.00
-20.00
-55.30
-31.40
ITC
2A9K_A_B
EB109A
EB65A
RIM
2A9K_A_B,5XCO_A_B
>1E-05
6E-08
Ras-related protein Ral-A
Mono-ADP-ribosyltransferase C3
310
None
None
None
None
ITC
4CPA_A_I
PI36G
PI35G
SUP
4CPA_A_I,2ABZ_B_E
1.2E-07
1.5E-09
Carboxypeptidase A
Potato carboxypeptidase inhibitor
298(assumed)
None
None
None
None
IASP
4CPA_A_I
GI35P,PI36G
GI34P,PI35G
INT,SUP
4CPA_A_I,2ABZ_B_E
unf
1.5E-09
Carboxypeptidase A
Potato carboxypeptidase inhibitor
298(assumed)
None
None
None
None
IASP
4CPA_A_I
YI37G
YI36G
COR
4CPA_A_I,2ABZ_B_E
3.5E-09
1.5E-09
Carboxypeptidase A
Potato carboxypeptidase inhibitor
298(assumed)
None
None
None
None
IASP
4CPA_A_I
YI37F
YI36F
COR
4CPA_A_I,2ABZ_B_E
1.5E-09
1.5E-09
Carboxypeptidase A
Potato carboxypeptidase inhibitor
298(assumed)
None
None
None
None
IASP
4CPA_A_I
VI38G
VI37G
COR
4CPA_A_I,2ABZ_B_E
8.2E-07
1.5E-09
Carboxypeptidase A
Potato carboxypeptidase inhibitor
298(assumed)
None
None
None
None
IASP
4CPA_A_I
VI38A
VI37A
COR
4CPA_A_I,2ABZ_B_E
7.6E-08
1.5E-09
Carboxypeptidase A
Potato carboxypeptidase inhibitor
298(assumed)
None
None
None
None
IASP
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