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PDBe
RCSB
PDBj
7085 records found
| PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt▲ | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2SIC_E_I | MI73A | MI67A | COR | Pr/PI | Pr/PI | 2.6E-11 | 1.8E-11 | Subtilisin BPN | Streptomyces subtilisin inhibitor | 298 | 3.7E+06 | 6.5E+06 | 1.4E-04 | 9E-05 | None | None | None | None | IASP | ||
| 2SIC_E_I | MI73L | MI67L | COR | Pr/PI | Pr/PI | 1.2E-11 | 1.8E-11 | Subtilisin BPN | Streptomyces subtilisin inhibitor | 298 | 4.2E+06 | 6.5E+06 | 2.1E-04 | 9E-05 | None | None | None | None | IASP | ||
| 2SIC_E_I | MI73V | MI67V | COR | Pr/PI | Pr/PI | 6E-11 | 1.8E-11 | Subtilisin BPN | Streptomyces subtilisin inhibitor | 298 | 5.4E+06 | 6.5E+06 | 3.5E-04 | 9E-05 | None | None | None | None | IASP | ||
| 2SIC_E_I | MI73I | MI67I | COR | Pr/PI | Pr/PI | 2.7E-10 | 1.8E-11 | Subtilisin BPN | Streptomyces subtilisin inhibitor | 298 | 6.2E+06 | 6.5E+06 | 1.7E-03 | 9E-05 | None | None | None | None | IASP | ||
| 1CZ8_HL_VW | LL4M,DH28T,HH31N,... | LL4M,DH28T,HH31N,... | INT,SUR,COR,COR,RIM | AB/AG | AB/AG | 2.9E-09 | <1.4E-10 | Fab-12 | VEGF | 298 | 4.1E+04 | 3.6E+04 | 1.2E-04 | <5E-06 | None | None | None | None | SPR |