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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut▲ | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3N0P_A_B | AA30H | AA17H | SUP | 3MZG_A_B,3N06_A_B... | 1.3E-08 | 2.4E-08 | Prolactin | Prolactin receptor | 298 | 9E+04 | 9.9E+04 | 1.2E-03 | 2.4E-03 | None | None | None | None | SPR | |||
3NCB_A_B | AA180H | AA167H | COR | 3MZG_A_B,3N06_A_B... | 1.3E-08 | 8.2E-07 | Prolactin | Prolactin receptor | 298 | 9E+04 | 6E+04 | 1.2E-03 | 4.9E-02 | None | None | None | None | SPR | |||
1REW_AB_C | AA34D,DA53A,AB34D... | AA23D,DA42A,AB23D... | SUR,COR,SUR,SUR | 1REW_AB_C,2QJ9_AB... | 4.89E-10 | 6.67E-10 | Bone morphogenetic protein-2 | BMPR-IA receptor | 298 | 9E+05 | 6E+05 | 4.4E-04 | 4E-04 | None | None | None | None | SPR | |||
1N8Z_AB_C | YB105F | YB105F | COR | AB/AG | AB/AG | 1.4E-09 | 3.5E-10 | Herceptin | erbB-2 | 310 | 9E+05 | 1E+06 | 1.3E-03 | 3.5E-04 | None | None | None | None | SPR | ||
3S9D_A_B | KA133A | KA104A | SUR | 3S9D_A_B,3SE3_B_C... | 3.7E-08 | 1E-08 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | 9E+05 | 2.1E+06 | 3.3E-02 | 2E-02 | None | None | None | None | SP |