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PDBe
RCSB
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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut▲ | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1TM1_E_I | RI65A | RI46A | INT | Pr/PI | Pr/PI | 3.62E-10 | 2E-12 | Subtilisin BPN | Chymotrypsin inhibitor 2 | 298 | 9.6E+05 | 3.1E+06 | 3.47E-04 | 6.1E-06 | None | None | None | None | SFFL | ||
2AK4_ABC_DE | TA69A | TA69A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.05E-05 | 1.87E-05 | HLA-B35 plus LPEP viral peptide | SB27 TCR | 298 | 9.79E+04 | 6.56E+04 | 9.4E-02 | 1.2E-01 | None | None | None | None | SPR | ||
3L5X_A_HL | NL92D,EL93W,YL94S | NL92D,EL93W,YL94S | RIM,SUR,SUR | AB/AG | AB/AG,3LB6_A_C | 2.25E-10 | 7.54E-10 | Interleukin-13 | H2L6 fab | 298 | 9.7E+05 | 1.25E+06 | 2.2E-04 | 9.4E-04 | None | None | None | None | SPR | ||
3L5X_A_HL | NL92S,EL93S,YL94G | NL92S,EL93S,YL94G | RIM,SUR,SUR | AB/AG | AB/AG,3LB6_A_C | 4.95E-10 | 7.54E-10 | Interleukin-13 | H2L6 fab | 298 | 9.7E+05 | 1.25E+06 | 4.8E-04 | 9.4E-04 | None | None | None | None | SPR | ||
1N8Z_AB_C | HA91F | HA91F | SUP | AB/AG | AB/AG | 3.7E-10 | 3.5E-10 | Herceptin | erbB-2 | 310 | 9.7E+05 | 1E+06 | 3.6E-04 | 3.5E-04 | None | None | None | None | SPR | ||
1JTG_A_B | YB53A | YB53A | SUP | 1XXM_A_C,1S0W_A_C... | 1.59E-07 | 4.77E-09 | TEM-1 beta-lactamase | BLIP | 298 | 9.82E+04 | 6.7E+04 | 8.27E-03 | 1.5E-04 | None | None | None | None | SPR | |||
1EMV_A_B | KA35A | KA33A | SUR | 2VLP_A_B,2VLN_A_B... | 2.24E-14 | 1.62E-14 | Colicin E9 immunity protein | Colicin E9 DNase | 298 | 9.82E+07 | 1.13E+08 | 2.2E-06 | 1.83E-06 | None | None | None | None | SFFL | |||
1AO7_ABC_DE | DA61A | DA61A | SUR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.67E-06 | 8.8E-07 | HLA-A2 plus tax peptide | A6 TCR | 298 | 9.836066E+04 | 1.2E+05 | 1.56E-01 | 1E-01 | None | None | None | None | SPR | ||
1AO7_ABC_DE | TA73A | TA73A | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 3.21E-06 | 8.8E-07 | HLA-A2 plus tax peptide | A6 TCR | 298 | 9.836066E+04 | 1.2E+05 | 2.98E-01 | 1E-01 | None | None | None | None | SPR | ||
2AK4_ABC_DE | QA65A | QA65A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.21E-05 | 1.87E-05 | HLA-B35 plus LPEP viral peptide | SB27 TCR | 298 | 9.85E+04 | 6.56E+04 | 1.35E-01 | 1.2E-01 | None | None | None | None | SPR |