SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
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!=
<
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<=
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in
not in
=
!=
<
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starts with
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not in
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<
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not in
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<
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<=
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starts with
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not in
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<
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<=
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starts with
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not in
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<
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<=
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starts with
contains
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not in
=
!=
<
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<=
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=
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<
>
<=
>=
=
!=
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=
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<
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<=
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=
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<
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<=
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1PPF_E_I
EI19T
EI19T
RIM
Pr/PI
Pr/PI
2.08E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19P
EI19P
RIM
Pr/PI
Pr/PI
3.7E-08
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19L
EI19L
RIM
Pr/PI
Pr/PI
1E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19I
EI19I
RIM
Pr/PI
Pr/PI
5.56E-10
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19M
EI19M
RIM
Pr/PI
Pr/PI
1.14E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19N
EI19N
RIM
Pr/PI
Pr/PI
1.27E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19D
EI19D
RIM
Pr/PI
Pr/PI
4.35E-10
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19K
EI19K
RIM
Pr/PI
Pr/PI
5.88E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19Q
EI19Q
RIM
Pr/PI
Pr/PI
5E-10
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19H
EI19H
RIM
Pr/PI
Pr/PI
5.26E-10
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
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