SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1R0R_E_I
EI19R
EI14R
COR
Pr/PI
Pr/PI
1E-09
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
EI19Y
EI14Y
COR
Pr/PI
Pr/PI
7.14E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
EI19W
EI14W
COR
Pr/PI
Pr/PI
6.67E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI19G
EI13G
RIM
Pr/PI
Pr/PI
6.25E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI19A
EI13A
RIM
Pr/PI
Pr/PI
1E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI19S
EI13S
RIM
Pr/PI
Pr/PI
4.76E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI19C
EI13C
RIM
Pr/PI
Pr/PI
1.3E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI19V
EI13V
RIM
Pr/PI
Pr/PI
2.22E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI19T
EI13T
RIM
Pr/PI
Pr/PI
6.67E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI19P
EI13P
RIM
Pr/PI
Pr/PI
8.33E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
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