SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
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!=
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<=
>=
starts with
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in
not in
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!=
<
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<=
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starts with
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in
not in
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<
>
<=
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starts with
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in
not in
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<
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<=
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not in
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<
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<=
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not in
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<=
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not in
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not in
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not in
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<
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<=
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starts with
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not in
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<
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<=
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starts with
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not in
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<
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<=
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starts with
contains
in
not in
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!=
<
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<=
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=
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<
>
<=
>=
=
!=
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=
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<
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<=
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=
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<
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<=
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1PPF_E_I
EI19F
EI19F
RIM
Pr/PI
Pr/PI
1.64E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19R
EI19R
RIM
Pr/PI
Pr/PI
2E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19Y
EI19Y
RIM
Pr/PI
Pr/PI
1.35E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
EI19W
EI19W
RIM
Pr/PI
Pr/PI
2.17E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
EI19G
EI14G
COR
Pr/PI
Pr/PI
2.86E-09
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
EI19A
EI14A
COR
Pr/PI
Pr/PI
1E-09
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
EI19S
EI14S
COR
Pr/PI
Pr/PI
6.25E-09
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
EI19C
EI14C
COR
Pr/PI
Pr/PI
1.61E-09
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
EI19V
EI14V
COR
Pr/PI
Pr/PI
3.45E-11
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
EI19T
EI14T
COR
Pr/PI
Pr/PI
3.85E-08
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
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