SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
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50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
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>=
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not in
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starts with
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not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
5F4E_A_B
KB163E
KB139E
RIM
5F4E_A_B
1.34E-07
5.9E-08
Sperm-egg fusion protein Izumo
Sperm-egg fusion protein Juno
293
1.81E+05
1.15E+05
2.42E-02
6.7E-03
None
None
None
None
BI
3SF4_A_D
RA221E
RA202E
SUP
3SF4_A_D,4G2V_A_B...
1.3E-07
2.4E-09
G-protein-signaling modulator 2 (LGN)
Protein inscuteable homolog (INSC)
298
None
None
None
None
SPR
3SF4_A_D
NA283R
NA264R
COR
3SF4_A_D,4G2V_A_B...
1.9E-08
2.4E-09
G-protein-signaling modulator 2 (LGN)
Protein inscuteable homolog (INSC)
298
None
None
None
None
SPR
3SF4_A_D
RA221E,NA283R
RA202E,NA264R
SUP,COR
3SF4_A_D,4G2V_A_B...
n.b
2.4E-09
G-protein-signaling modulator 2 (LGN)
Protein inscuteable homolog (INSC)
298
None
None
None
None
SPR
3SF4_A_D
WD31A
WD8A
COR
3SF4_A_D,4G2V_A_B...
4.3E-07
2.4E-09
G-protein-signaling modulator 2 (LGN)
Protein inscuteable homolog (INSC)
298
None
None
None
None
SPR
3SF4_A_D
ED42R
ED19R
COR
3SF4_A_D,4G2V_A_B...
6.2E-08
2.4E-09
G-protein-signaling modulator 2 (LGN)
Protein inscuteable homolog (INSC)
298
None
None
None
None
SPR
3SF4_A_D
KD50D
KD27D
COR
3SF4_A_D,4G2V_A_B...
4.8E-09
2.4E-09
G-protein-signaling modulator 2 (LGN)
Protein inscuteable homolog (INSC)
298
None
None
None
None
SPR
3SF4_A_D
WD31A,ED42R
WD8A,ED19R
COR,COR
3SF4_A_D,4G2V_A_B...
n.b
2.4E-09
G-protein-signaling modulator 2 (LGN)
Protein inscuteable homolog (INSC)
298
None
None
None
None
SPR
4G2V_A_B
RA221E
RA198E
SUP
4G2V_A_B,3SF4_A_D...
4.8E-06
1.1E-07
G-protein-signaling modulator 2 (LGN)
FERM and PDZ domain-containing protein 1 (FRMPD1) peptide
298
None
None
None
None
SPR
4G2V_A_B
NA283R
NA260R
SUR
4G2V_A_B,3SF4_A_D...
1.6E-07
1.1E-07
G-protein-signaling modulator 2 (LGN)
FERM and PDZ domain-containing protein 1 (FRMPD1) peptide
298
None
None
None
None
SPR
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