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7085 records found
| PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1OGA_ABC_DE | DE56A | DE52A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 6.21E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -24.00 | -23.00 | -57.00 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | QE58A | QE54A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.22E-05 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -18.00 | -23.00 | -36.90 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | QE58E | QE54E | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.24E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -20.00 | -23.00 | -43.60 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | SE99A | SE95A | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.24E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -18.00 | -23.00 | -33.50 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | YE101A | YE97A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 7.35E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -29.00 | -23.00 | -73.80 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | YE101F | YE97F | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.22E-05 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -20.00 | -23.00 | -43.60 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | SD32A | SD30A | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 2.84E-05 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -24.00 | -23.00 | -60.40 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | QD34A | QD32A | INT | TCR/pMHC | TCR/pMHC,1JCK_A_B | 2.84E-05 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -23.00 | -23.00 | -57.00 | -50.30 | ITC | ||||||
| 2P5E_ABC_DE | TD51P,PD52F,AE49S... | TD52P,PD53F,AE49S... | SUP,INT,COR,COR,R... | TCR/pMHC | TCR/pMHC,1JCK_A_B... | 1.31E-09 | 4.77E-11 | HLA-A2 plus NY-ESO peptide | 1G4 TCR | 298(assumed) | 1.81E+05 | 5.7E+05 | 2.37E-04 | 2.72E-05 | None | None | None | None | SPR | ||
| 2P5E_ABC_DE | TD51Q,PD52S,WD53S... | TD52Q,PD53S,WD54S... | SUP,INT,COR,COR,C... | TCR/pMHC | TCR/pMHC,1JCK_A_B... | 8.15E-08 | 4.77E-11 | HLA-A2 plus NY-ESO peptide | 1G4 TCR | 298(assumed) | 1.78E+04 | 5.7E+05 | 1.45E-03 | 2.72E-05 | None | None | None | None | SPR |