SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
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50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
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7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
4G2V_A_B
RA221E,NA283R
RA198E,NA260R
SUP,SUR
4G2V_A_B,3SF4_A_D...
5.2E-06
1.1E-07
G-protein-signaling modulator 2 (LGN)
FERM and PDZ domain-containing protein 1 (FRMPD1) peptide
298
None
None
None
None
SPR
4WND_A_B
RA221E
RA201E
SUP
4WND_A_B,3SF4_A_D...
6.5E-06
5.8E-08
G-protein-signaling modulator 2 (LGN)
FERM and PDZ domain-containing protein 4 (FRMPD4)
298
None
None
None
None
SPR
4WND_A_B
NA283R
NA263R
COR
4WND_A_B,3SF4_A_D...
5.6E-08
5.8E-08
G-protein-signaling modulator 2 (LGN)
FERM and PDZ domain-containing protein 4 (FRMPD4)
298
None
None
None
None
SPR
4WND_A_B
RA221E,NA283R
RA201E,NA263R
SUP,COR
4WND_A_B,3SF4_A_D...
3.9E-05
5.8E-08
G-protein-signaling modulator 2 (LGN)
FERM and PDZ domain-containing protein 4 (FRMPD4)
298
None
None
None
None
SPR
2VLR_ABC_DE
AE99S
AE95S
SUP
TCR/pMHC
TCR/pMHC,1JCK_A_B
5.2E-06
4.9E-06
HLA-A2 plus flu peptide
JM22 TCR
298
3.1E+04
5.9E+04
1.6E-01
2.9E-01
None
None
None
None
SPR
1OGA_ABC_DE
DE32A
DE28A
COR
TCR/pMHC
TCR/pMHC,1JCK_A_B
7.4E-05
5.2E-06
HLA-A2 plus flu peptide
JM22 TCR
298
None
None
None
None
SPR
1OGA_ABC_DE
DE32S
DE28S
COR
TCR/pMHC
TCR/pMHC,1JCK_A_B
>2E-04
5.2E-06
HLA-A2 plus flu peptide
JM22 TCR
298
None
None
None
None
SPR
1OGA_ABC_DE
QE52A
QE48A
COR
TCR/pMHC
TCR/pMHC,1JCK_A_B
>2E-04
5.2E-06
HLA-A2 plus flu peptide
JM22 TCR
298
None
None
None
None
SPR
1OGA_ABC_DE
QE52E
QE48E
COR
TCR/pMHC
TCR/pMHC,1JCK_A_B
>2E-04
5.2E-06
HLA-A2 plus flu peptide
JM22 TCR
298
None
None
None
None
SPR
1OGA_ABC_DE
IE53A
IE49A
COR
TCR/pMHC
TCR/pMHC,1JCK_A_B
>2E-04
5.2E-06
HLA-A2 plus flu peptide
JM22 TCR
298
None
None
None
None
SPR
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