SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)	Kon Mut	Kon Wt	Koff Mut	Koff Wt	Dh Mut	Dh Wt	Ds Mut	Ds Wt	Method
1N8Z_AB_C	LC525A	LC509A	SUR	AB/AG	AB/AG	1.26E-09	1.31E-09	Herceptin	erbB-2	298	1.04E+05	1.19E+05	1.32E-04	1.56E-04	None	None	None	None	SPR
1N8Z_AB_C	SC551A	SC535A	SUR	AB/AG	AB/AG	1.38E-09	1.31E-09	Herceptin	erbB-2	298	1.07E+05	1.19E+05	1.47E-04	1.56E-04	None	None	None	None	SPR
1N8Z_AB_C	VC552A	VC536A	SUR	AB/AG	AB/AG	1.33E-09	1.31E-09	Herceptin	erbB-2	298	9.6E+04	1.19E+05	1.28E-04	1.56E-04	None	None	None	None	SPR
1N8Z_AB_C	FC555A	FC539A	SUR	AB/AG	AB/AG	1.39E-09	1.31E-09	Herceptin	erbB-2	298	1.06E+05	1.19E+05	1.48E-04	1.56E-04	None	None	None	None	SPR
3R9A_AC_B	AA328W	AA323W	RIM		3R9A_AC_B,2C0L_A_B	6.2E-06	3.5E-06	Alanine-glyoxylate aminotransferase	PEX5P	298					6.31	3.80	45.00	37.70	ITC
3R9A_AC_B	YA330A	YA325A	SUP		3R9A_AC_B,2C0L_A_B	1.94E-05	3.5E-06	Alanine-glyoxylate aminotransferase	PEX5P	298					3.97	3.80	35.00	37.70	ITC
3R9A_AC_B	YA330W	YA325W	SUP		3R9A_AC_B,2C0L_A_B	7.9E-06	3.5E-06	Alanine-glyoxylate aminotransferase	PEX5P	298					5.59	3.80	42.20	37.70	ITC
3R9A_AC_B	VA336D	VA331D	INT		3R9A_AC_B,2C0L_A_B	3.5E-06	3.5E-06	Alanine-glyoxylate aminotransferase	PEX5P	298					4.11	3.80	38.80	37.70	ITC
3R9A_AC_B	GA170R	GA165R	INT		3R9A_AC_B,2C0L_A_B	3.8E-06	3.5E-06	Alanine-glyoxylate aminotransferase	PEX5P	298					4.52	3.80	39.90	37.70	ITC
3G6D_LH_A	FH103A,HH104A,WH105A	FH103A,HH104A,WH105A	COR,COR,COR	AB/AG	AB/AG,3LB6_A_C	n.b	1.84E-11	CNTO607 fab	Interleukin-13	298					None	None	None	None	SPR