SKEMPI v2.0

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Mutations

7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt▲	Ref.	Protein 1	Protein 2	T (ºK)	Kon Mut	Kon Wt	Koff Mut	Koff Wt	Dh Mut	Dh Wt	Ds Mut	Ds Wt	Method
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,COR,R...	AB/AG	AB/AG	9E-09	<1.4E-10		Fab-12	VEGF	298	3E+04	4.1E+04	2.7E-04	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,COR,R...	AB/AG	AB/AG	3.3E-09	<1.4E-10		Fab-12	VEGF	298	5.2E+04	4.1E+04	1.7E-04	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,YH54W	LL4M,YH54W	INT,RIM	AB/AG	AB/AG	3.8E-10	<1.4E-10		Fab-12	VEGF	298	4E+04	4.1E+04	1.5E-05	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M	LL4M	INT	AB/AG	AB/AG	<1.5E-10	<1.4E-10		Fab-12	VEGF	298	3.5E+04	4.1E+04	<5E-06	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,HH31N,YH101H...	LL4M,HH31N,YH101H...	INT,COR,COR,RIM	AB/AG	AB/AG	2E-09	<1.4E-10		Fab-12	VEGF	298	6.8E+04	4.1E+04	1.4E-04	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,YH101H...	LL4M,DH28T,YH101H...	INT,SUR,COR,RIM	AB/AG	AB/AG	8E-10	<1.4E-10		Fab-12	VEGF	298	4.8E+04	4.1E+04	3.7E-05	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,RIM	AB/AG	AB/AG	2E-10	<1.4E-10		Fab-12	VEGF	298	2.5E+04	4.1E+04	4.5E-06	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,COR	AB/AG	AB/AG	1.5E-09	<1.4E-10		Fab-12	VEGF	298	6.8E+04	4.1E+04	1E-04	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,RIM,R...	AB/AG	AB/AG	<5.4E-10	<1.4E-10		Fab-12	VEGF	298					None	None	None	None	SPR
4I77_HL_Z	YH97F	YH100F	RIM	AB/AG	AB/AG	<1E-11	<1E-11		Lebrikizumab fab	Interleukin-13	298					None	None	None	None	SPR