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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt▲ | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1CBW_FGH_I | GI37A | GI37A | COR | Pr/PI | Pr/PI | 5.49E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 3.60 | 2.50 | 45.70 | 44.70 | ITC | ||||||
1CBW_FGH_I | RI39A | RI39A | RIM | Pr/PI | Pr/PI | 1.99E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 3.10 | 2.50 | 46.10 | 44.70 | ITC | ||||||
1CBW_FGH_I | KI46A | KI46A | SUR | Pr/PI | Pr/PI | 1.68E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 2.30 | 2.50 | 43.70 | 44.70 | ITC | ||||||
3EG5_A_B | HA104F | HA104F | COR | 3EG5_A_B,1GRN_A_B... | 3.7E-08 | 1.25E-06 | M. musculus Cdc42 | MdiaN-TSH | 293 | -0.67 | 3.28 | 31.7064846416 | 38.2252559727 | ITC | |||||||
3EG5_A_B | TB164N,SB165N,HB166N | TB73N,SB74N,HB75N | COR,COR,SUP | 3EG5_A_B,1GRN_A_B... | 7.4E-06 | 1.25E-06 | M. musculus Cdc42 | MdiaN-TSH | 293 | 2.20 | 3.28 | 31.023890785 | 38.2252559727 | ITC | |||||||
3EG5_A_B | TB164N,SB165N,HB1... | TB73N,SB74N,HB75N... | COR,COR,SUP,COR | 3EG5_A_B,1GRN_A_B... | 1.33E-07 | 1.25E-06 | M. musculus Cdc42 | MdiaN-TSH | 293 | -1.60 | 3.28 | 26.0068259386 | 38.2252559727 | ITC | |||||||
2HLE_A_B | KA149Q | KA141Q | COR | 2HLE_A_B,4L0P_A_B | 2E-08 | 4E-08 | Ephrin type-B receptor 4 | Ephrin-B2 | 298 | 3.70 | 3.30 | 48.30 | 44.90 | ITC | |||||||
2HLE_A_B | LA95R | LA87R | SUP | 2HLE_A_B,4L0P_A_B | 1.9E-06 | 4E-08 | Ephrin type-B receptor 4 | Ephrin-B2 | 298 | 5.20 | 3.30 | 43.60 | 44.90 | ITC | |||||||
3R9A_AC_B | AA328W | AA323W | RIM | 3R9A_AC_B,2C0L_A_B | 6.2E-06 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 6.31 | 3.80 | 45.00 | 37.70 | ITC | |||||||
3R9A_AC_B | YA330A | YA325A | SUP | 3R9A_AC_B,2C0L_A_B | 1.94E-05 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 3.97 | 3.80 | 35.00 | 37.70 | ITC |