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PDBe
RCSB
PDBj
7085 records found
PDB Code | Mutation Pdb▲ | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1B3S_A_D | AA102H | AA102H | COR | 1BRS_A_D,1B2U_A_D... | 8E-15 | 1.17E-10 | Barnase | Barstar | 298 | 3E+08 | 3.9E+08 | 2.4E-06 | 4.5E-02 | None | None | None | None | SFFL | |||
1B3S_A_D | AA102H,FD30Y | AA102H,FD30Y | COR,RIM | 1BRS_A_D,1B2U_A_D... | 1E-14 | 1.17E-10 | Barnase | Barstar | 298 | 3.7E+08 | 3.9E+08 | 3.7E-06 | 4.5E-02 | None | None | None | None | SFFL | |||
1FFW_A_B | AA103V | AA102V | SUP | 1FFW_A_B | 1.23E-05 | 1.23E-06 | Chemotaxis protein CheY | Chemotaxis protein CheA | 298 | -8.40 | -12.00 | -5.60 | -13.00 | ITC | |||||||
3S9D_A_B | AA145G | AA116G | COR | 3S9D_A_B,3SE3_B_C... | 1E-07 | 3E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | 2.9E+06 | 3.7E+06 | 2.88E-01 | 1.1E-02 | None | None | None | None | SP | |||
3S9D_A_B | AA145G | AA116G | COR | 3S9D_A_B,3SE3_B_C... | 1E-07 | 3E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | None | None | None | None | SPR | |||||||
3S9D_A_B | AA145G | AA116G | COR | 3S9D_A_B,3SE3_B_C... | 9.6E-08 | 2.5E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | None | None | None | None | SP | |||||||
3S9D_A_B | AA145M | AA116M | COR | 3S9D_A_B,3SE3_B_C... | 1.79E-08 | 3E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | 4.4E+06 | 3.7E+06 | 7.9E-02 | 1.1E-02 | None | None | None | None | SP | |||
3S9D_A_B | AA145M | AA116M | COR | 3S9D_A_B,3SE3_B_C... | 1.88E-08 | 3E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | None | None | None | None | SPR | |||||||
2BNR_ABC_DE | AA149G | AA149G | RIM | TCR/pMHC | TCR/pMHC,1JCK_A_B... | 3.3E-06 | 3.2E-06 | HLA-A2 plus NY-ESO peptide | 1G4 TCR | 298 | 2.5E+04 | 2.4E+04 | 1.08E-01 | 1E-01 | None | None | None | None | SPR | ||
1AO7_ABC_DE | AA149G | AA149G | RIM | TCR/pMHC | TCR/pMHC,1JCK_A_B | 6.78E-07 | 8.8E-07 | HLA-A2 plus tax peptide | A6 TCR | 298 | 1.5E+05 | 1.2E+05 | 9.7E-02 | 1E-01 | None | None | None | None | SPR |