SKEMPI v2.0

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Mutations

7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Ref.	Protein 1	Protein 2	T (ºK)	Kon Mut	Kon Wt	Koff Mut	Koff Wt	Dh Mut	Dh Wt	Ds Mut	Ds Wt	Method
3NGB_HL_G	IH30T	IH30T	COR	AB/AG	AB/AG	6.52E-09	5.76E-09		VRC01 fab	gp120	298	4.79E+04	3.83E+04	3.12E-04	2.2E-04	None	None	None	None	SPR
3NGB_HL_G	KH52N	KH52N	COR	AB/AG	AB/AG	7.74E-09	5.76E-09		VRC01 fab	gp120	298	4.53E+04	3.83E+04	3.5E-04	2.2E-04	None	None	None	None	SPR
3NGB_HL_G	RH53N	RH54N	RIM	AB/AG	AB/AG	6.23E-09	5.76E-09		VRC01 fab	gp120	298	7.06E+04	3.83E+04	4.4E-04	2.2E-04	None	None	None	None	SPR
3NGB_HL_G	RH61Q	RH62Q	COR	AB/AG	AB/AG	6.78E-09	5.76E-09		VRC01 fab	gp120	298	4.3E+04	3.83E+04	2.92E-04	2.2E-04	None	None	None	None	SPR
3NGB_HL_G	YL28S	YL26S	RIM	AB/AG	AB/AG	1.73E-08	5.76E-09		VRC01 fab	gp120	298	4.73E+04	3.83E+04	8.2E-04	2.2E-04	None	None	None	None	SPR
3NGB_HL_G	AH56G,VH57T,PH62K...	AH57G,VH58T,PH63K...	COR,COR,RIM,COR	AB/AG	AB/AG	9.72E-08	5.76E-09		VRC01 fab	gp120	298	7.225E+03	3.83E+04	7.02E-04	2.2E-04	None	None	None	None	SPR
3NGB_HL_G	TH33Y,GH55S,AH56G...	TH33Y,GH56S,AH57G...	SUP,SUP,COR,COR,R...	AB/AG	AB/AG	1.52E-07	5.76E-09		VRC01 fab	gp120	298	3.732E+03	3.83E+04	5.67E-04	2.2E-04	None	None	None	None	SPR
3NGB_HL_G	IH30T,KH52N,RH53N...	IH30T,KH52N,RH54N...	COR,COR,RIM,COR,C...	AB/AG	AB/AG	2.47E-08	5.76E-09		VRC01 fab	gp120	298	6.32E+03	3.83E+04	1.56E-04	2.2E-04	None	None	None	None	SPR
3NGB_HL_G	CH32S,CH98A	CH32S,CH102A	INT,SUR	AB/AG	AB/AG	8.92E-09	5.76E-09		VRC01 fab	gp120	298	3.87E+04	3.83E+04	3.45E-04	2.2E-04	None	None	None	None	SPR
3S9D_A_B	SA25A	SA18A	RIM		3S9D_A_B,3SE3_B_C...	7E-09	1E-08		Interferon alpha-2	Interferon alpha/beta receptor 2	298(assumed)	2.1E+06	2.1E+06	1.5E-02	2E-02	None	None	None	None	SP