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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut▲ | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2PCB_A_B | EA291Q | EA291Q | SUR | 2PCB_A_B,2B0Z_A_B... | 9.09E-06 | 1E-05 | Cytochrome C peroxidase | Non-cognate Cytochrome C | 298 | 2.13 | 2.25 | 30.10 | 30.80 | ITC | |||||||
1BRS_A_D | EA73W,ED76A | EA71W,ED74A | SUP,RIM | 1BRS_A_D,1B2U_A_D... | 4E-12 | 1E-14 | Barnase | Barstar | 298 | -6.50 | -19.30 | 30.20 | -1.01 | ITC | |||||||
3EG5_A_B | TB164N,SB165N,HB166N | TB73N,SB74N,HB75N | COR,COR,SUP | 3EG5_A_B,1GRN_A_B... | 7.4E-06 | 1.25E-06 | M. musculus Cdc42 | MdiaN-TSH | 293 | 2.20 | 3.28 | 31.023890785 | 38.2252559727 | ITC | |||||||
1BRS_A_D | EA73A | EA71A | SUP | 1BRS_A_D,1B2U_A_D... | 5.26E-13 | 1E-14 | Barnase | Barstar | 298 | -7.30 | -19.30 | 31.50 | -1.01 | ITC | |||||||
3EG5_A_B | HA104F | HA104F | COR | 3EG5_A_B,1GRN_A_B... | 3.7E-08 | 1.25E-06 | M. musculus Cdc42 | MdiaN-TSH | 293 | -0.67 | 3.28 | 31.7064846416 | 38.2252559727 | ITC | |||||||
1BRS_A_D | EA73A,DD35A | EA71A,DD35A | SUP,COR | 1BRS_A_D,1B2U_A_D... | 5.26E-10 | 1E-14 | Barnase | Barstar | 298 | -3.00 | -19.30 | 32.20 | -1.01 | ITC | |||||||
1CBW_FGH_I | GI12A | GI12A | SUP | Pr/PI | Pr/PI | 3.92E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | -0.60 | 2.50 | 32.20 | 44.70 | ITC | ||||||
1JTG_A_B | SB71A | SB71A | SUP | 1XXM_A_C,1S0W_A_C... | 3.01E-10 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 303 | -3.20 | -7.40 | 33.00330033 | 21.10 | ITC | |||||||
3R9A_AC_B | YA330A | YA325A | SUP | 3R9A_AC_B,2C0L_A_B | 1.94E-05 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 3.97 | 3.80 | 35.00 | 37.70 | ITC | |||||||
3R9A_AC_B | VA336D | VA331D | INT | 3R9A_AC_B,2C0L_A_B | 3.5E-06 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 4.11 | 3.80 | 38.80 | 37.70 | ITC |