SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)	Dh Mut	Dh Wt	Ds Mut▲	Ds Wt	Method
1JTG_A_B	YB50A	YB50A	COR		1XXM_A_C,1S0W_A_C...	3.1E-12	1.11E-10	TEM-1 beta-lactamase	BLIP	288	-3.90	-7.40	39.1180324956	21.10	ITC
1CBW_FGH_I	YI35A	YI35A	INT	Pr/PI	Pr/PI	5.49E-08	1.42E-08	Bovine alpha-chymotrypsin	BPTI	295	1.80	2.50	39.60	44.70	ITC
3R9A_AC_B	GA170R	GA165R	INT		3R9A_AC_B,2C0L_A_B	3.8E-06	3.5E-06	Alanine-glyoxylate aminotransferase	PEX5P	298	4.52	3.80	39.90	37.70	ITC
1CBW_FGH_I	KI15A	KI15A	COR	Pr/PI	Pr/PI	4.17E-07	1.42E-08	Bovine alpha-chymotrypsin	BPTI	295	3.40	2.50	41.00	44.70	ITC
3R9A_AC_B	YA330W	YA325W	SUP		3R9A_AC_B,2C0L_A_B	7.9E-06	3.5E-06	Alanine-glyoxylate aminotransferase	PEX5P	298	5.59	3.80	42.20	37.70	ITC
1CBW_FGH_I	GI36A	GI36A	SUP	Pr/PI	Pr/PI	6.5E-08	1.42E-08	Bovine alpha-chymotrypsin	BPTI	295	3.00	2.50	43.40	44.70	ITC
2HLE_A_B	LA95R	LA87R	SUP		2HLE_A_B,4L0P_A_B	1.9E-06	4E-08	Ephrin type-B receptor 4	Ephrin-B2	298	5.20	3.30	43.60	44.90	ITC
1CBW_FGH_I	RI20A	RI20A	INT	Pr/PI	Pr/PI	2.36E-08	1.42E-08	Bovine alpha-chymotrypsin	BPTI	295	2.50	2.50	43.70	44.70	ITC
1CBW_FGH_I	KI46A	KI46A	SUR	Pr/PI	Pr/PI	1.68E-08	1.42E-08	Bovine alpha-chymotrypsin	BPTI	295	2.30	2.50	43.70	44.70	ITC
3QFJ_ABC_DE	FC5Y	FC5Y	COR	TCR/pMHC	TCR/pMHC,1JCK_A_B	9E-07	1.2E-06	HLA-A2 plus tax peptide	A6 TCR	277	4.40	5.90	44.00	48.00	ITC